AGITG TOP GEAR: A Randomised Phase II/III Trial of Preoperative Chemoradiotherapy Versus Preoperative Chemotherapy for Resectable Gastric Cancer

Preoperative Chemoradiotherapy for Resectable Gastric Cancer

T Leong, BM Smithers, M Michael, K Haustermans, R Wong, V Gebski, RL O’Connell, J Zalcberg, A Boussioutas, M Findlay, D Willis, A Moore, WK Murray, F Lordick, C O’Callaghan, C Swallow, G Darling, D Miller, A Strickland, M Liberman

2024-11-14

BACKGROUND In Western countries, the current standard of care for resectable gastric cancer is perioperative chemotherapy. Preoper..

LBA58 A randomized phase III trial of perioperative chemotherapy (periop CT) with or without preoperative chemoradiotherapy (preop CRT) for resectable gastric cancer (AGITG TOPGEAR): Final results from an intergroup trial of AGITG, TROG, EORTC and CCTG

T Leong, BM Smithers, M Michael, KM Haustermans, R Wong, V Gebski, R O'Connell, JR Zalcberg, A Boussioutas, M Findlay, D Willis, A Moore, F Lordick, C O'Callaghan, C Swallow, GE Darling, A Strickland, M Liberman, L Mineur, J Simes

2024-09-01

The Feasibility of Quality Assurance in the TOPGEAR International Phase 3 Clinical Trial of Neoadjuvant Chemoradiation Therapy for Gastric Cancer (an Intergroup Trial of the AGITG/TROG/NHMRC CTC/EORTC/CCTG)

J Lukovic, AJ Moore, MT Lee, D Willis, S Ahmed, M Akra, E Hortobagyi, T Kron, D Lim Joon, A Liu, J Ryan, M Thomas, K Wall, I Ward, KL Wiltshire, CJ O'Callaghan, RKS Wong, JG Ringash, K Haustermans, T Leong

2023-12-01

Purpose: The TOPGEAR phase 3 trial hypothesized that adding preoperative chemoradiation therapy (CRT) to perioperative chemotherap..